Essays About Stem Cell Research Ethics

Essays About Stem Cell Research Ethics-47
The combined qualitative and quantitative results were translated into an interactive website and thematic content where researchers could navigate using portholes that addressed the ethics of different stages of translational SCR. Stem cell researchers should avoid providing medical advice to patients and instead encourage patients to seek medical advice from physicians, direct them to ].The content of the website was developed by topic experts (some of whom participated in the needs assessment) and was updated regularly until the end of its funding in 2016. Another topic of significance for stem cell researchers surrounds the use of human biological materials as a potential source of stem cells.While it is beyond the scope of this paper to describe content analysis and other methodologies discussed, we refer readers to several excellent sources []. While originally unproven stem cell interventions were thought to be offered in countries with lax regulatory standards [].

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The aim of ethics education for stem cell researchers is to understand the ELSI of SCR, develop a sense of moral responsibility of research, understand the ethical conduct of scientific research, and develop ethical reasoning skills. Our approach to teaching stem cell ethics and policy is to focus on some of the principles and ethical issues surrounding SCR (Table ).

Our approach to developing an ethics training program containing three important elements is as follows: (1) needs assessment, (2) robust course design, and (3) course evaluation. Earlier debates surrounding SCR focused on the moral status of human embryos and whether embryos can be created for research purposes while current issues surround patenting and commercialization, privacy protections of embryo donors, and unproven stem cell interventions (a.k.a. An ELSI course on SCR can cover several of these topics, the public communication of SCR, and the policies and practices of SCR.

Stem cell research is an exciting field with clinical potential and has been rapidly moving towards the goal of translating research into therapeutics. A critical issue for (a) is whether animal use provides a good model for reaching findings relevant to human health.

Like all scientific fields, there are many ethical, legal, and social issues (ELSI) associated with stem cell research and stem cell scientists, especially trainees, should be aware of them. In some cases, concerns about scientific validity and relevance of particular animal models to human health are raised [].This paper is meant to be a practical guide for course directors interested in developing ELSI pedagogy for stem cell scientists. An Introduction to the Principles of Morals and Legislation. The ethics of RIHs has a developed set of mainstream values and norms.The rapid growth of stem cell research (SCR) makes it an exciting field not only for its clinical potential but also because of the rich ethical, legal/policy and social issues (ELSI). The four biomedical ethics principles—autonomy, non-maleficience, beneficence, and justice—serve as the foundation for specific norms and practices for RIHs. (2000) provide a checklist of norms specific to ethical RIHs: scientific/clinical value, scientific validity, fair subject selection, favorable risk-benefit ratio, informed consent, protecting privacy, withdrawal, and undertaking regulatory review [ and regulatory documents such as the US Common Rule.Two authors of this paper undertook a needs assessment to develop an online, nationwide ethics course for stem cell scientists based on a grant awarded by Canada’s Stem Cell Network []. The ISSCR guidelines outline that SCR scientists “should promote accurate, balanced, and responsive public representations of stem cell research” [].The aim was to understand the topics and their importance to the Canadian SCR community. Scientists should be made aware of the problems of hyping science and should take care in the accurate portrayal of the state of SCR.This phase involves research and data collection using social science methods to help instructors understand the needs and receive buy-in from different stakeholders, understand institutional culture, work within budget, and design an effective course/program and tools to evaluate effectiveness []. The strengths and weaknesses of these moral theories can be discussed to show the intractability of the debate surrounding the moral status of embryos.In the absence of this effort, ethics education might be created to address issues important to its creators or one party instead of the needs of scientists. Beyond questions of moral status, earlier ethical debates surrounding SCR honed in on the potential physical and social harms to women as egg providers [].In this paper, we outline an ethics curriculum for stem cell scientists being mindful that much of the subject topics discussed form a core basis of ethics education for all biomedical scientists. These can be used to encourage discussion of the responsibilities of researchers and research teams towards participants.We draw on the academic and gray literature and our collective experiences in helping formulate our perspective with the practical goal to help faculty further reflect on how to design an ELSI curriculum for stem cell scientists. The ethics of SCR is captured under the umbrella of the ethics of RIHs, but there remain many unique elements to SCR that deserve special attention in a separate course.We cover elements of course design, content and venue, and course evaluation. While there is considerable variance in international regulatory regimes for RIAs, guiding principles are set in terms of “the three Rs” enunciated by Russell and Burch: Once these more fundamental issues are on the table, the stage is set for discussing specific responsibilities of researchers and research institutions in regard to the use of RIAs.Lastly, we broadly discuss course topics including the responsible conduct of research, ethics of research involving animals and humans, and stem cell ethics and policy. Here, as elsewhere, it is useful to discuss current and previous examples from stem cell and allied areas of research which include creating animal-human chimeras, hybrids, and germline transfer using adult and pluripotent stem cells.


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